The Syrian Observatory for Human Rights based in Britain said 45 opposition fighters and 43 regime forces had been killed in the fighting that began on Thursday.
Observatory director Rami Abdel Rahman told AFP that rebel forces, including fighters from Al-Qaeda's Syria affiliate Al-Nusra Front, had seized the strategic Tal al-Jabiyeh hill on Thursday.
Clashes were continuing as the opposition fighters sought to take another hilltop nearby in a bid to connect territory they hold in Daraa and the Quneitra region, alongside the Israeli-occupied Golan Heights.
Today, Abdel Rahman said, the opposition was focusing its efforts on capturing Tal Jamu, some five kilometres from Tal al-Jabiyeh, in a bid to link areas under its control.