He was 87.
Krishnamurthy, who was reportedly undergoing treatment for lung cancer, died at around 1.38 AM, family members said.
Expressing deep grief over his death, Andhra Pradesh Chief Minister N Chandrababu Naidu described him as a doyen in the field of Carnatic music.
"He did yeomen service to the spread of Carnatic Music and was the person under whose guidance Dr MS Subbalakshmi rendered the 'Annamacharya Keerthanas' in the TTD (Tirumala Tirupati Devasthanams) project. He was instrumental in organising the 'Naada Nirajanam Programme'. He was also Principal of the Music College and rendered great service in the field of Carnatic Music," Naidu noted in his condolence message.