The Aleppo Media Center activist group and the Britain-based Syrian Observatory for Human Rights said the strike hit the Seif al-Dawla neighborhood in Aleppo. The city, once the country's largest, has been divided between government and opposition forces since mid-2012.
The Observatory said seven people were killed, including four children. The Aleppo Media center put the death toll at more than 10 and said around 20 people were wounded. Differences in death tolls are common in the chaotic aftermath of attacks in Syria.
Outside the capital, meanwhile, heavy fighting raged in and around the town of Maydaa between Syrian government forces and rebels. Activists say Maydaa is a key supply route out of the sprawling rural area known as eastern Ghouta, which has long been under government siege.
The Syrian state news agency said army troops had "tightened their grip" on Maydaa and farms in the surrounding area. The Observatory said government forces had captured a majority of the town but that fighting was still taking place.