The 'Indiana Jones' star suffered "moderate injuries" in the accident when his plane suffered an engine failure and he was forced to make an emergency landing at Penmar golf course.
Ford, 72, a long time aviator, reportedly veered off course to avoid crashing into houses.
He was attended by two doctors who were already at the scene while the emergency personnel arrived. He was taken to a nearby hospital.
The actor was "alert and conscious" after suffering "moderate trauma", according to Patrick Butler, Los Angeles assistant fire chief.
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"Harrison was flying a WW2 vintage plane today which stalled upon takeoff. He had no other choice but to make an emergency landing, which he did safely. The injuries sustained are not life-threatening, and he is expected to make a full recovery," the rep told the website.
Ford's son Ben later tweeted, "At the hospital. Dad is ok. Battered, but ok! He is every bit the man you would think he is."
The Star Wars actor started talking to Santa Monica Airport control tower moments after taking off. He reported an engine failure and requested an emergency return to the airport.
The actor, who is all set to reprise his role in the 'Blade Runner' sequel and will be next seen in the next Star Wars sequel, survived a bad crash in 1999 where he escaped without injuries.
In 2000, he made an emergency landing. Ford broke his leg while shooting for Star Wars last year.