The 36-year-old singer revealed he had got a throat problem and was unable to perform on doctors orders, reported Daily Mirror.
"I am really sorry not to be able to perform tonight, but I have been told to rest up by the doctor. As a band we always want to give every performance our all and sadly I just cannot do that tonight," he said in a statement.
A spokeswoman from the Arena confirmed to the Liverpool Echo there were already fans arriving at the arena for the long-awaited gig.