The Manila-based bank would provide the financial assistance for the USD 500 million project, which will be located around 150 kilometers west from here on the Seti River in Tanahu district, that will generate electricity year round.
"Nepal has an energy crisis, and this is affecting badly economic prospects," said Yongping Zhai, Director, Energy Division in ADB's South Asia Department.
This energy project is a means to stop this crisis, he added.
"Blackouts of up to 18 hours a day in the dry season are common, even in the capital Kathmandu. This forces businesses and households to use expensive and polluting diesel generators," ADB said in a statement.
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Nepal's mountain ranges and many swiftly flowing rivers endow it with huge hydropower resources.
However, the country's total installed power generation capacity is just 700 megawatts � largely from hydropower, which represents only 1.5 per cent of Nepal's hydropower potential.
To ensure steady supply even during the dry winter months of November through April, the plant will be fed from a 7.26 square kilometer reservoir, making it Nepal's first major hydropower plant with water storage capacity and a sediment flushing system.
The total cost of the project comes around USD 500 million and will be co-funded by ADB and the Japan International Cooperation Agency lending, the European Investment Bank, and the Abu Dhabi Fund for Development.