"Yeah, I want to tell that lady as well, can you stop filming me with a video camera because I'm really here in real life," Adele said, pointing out the culprit to the audience while they cheered her along.
"You can enjoy it in real life, rather than through your camera."
Over more cheers and applause, Adele continued her take down - and in her defence it did sound like this fan had quite the filming set up going on, reported Digital Spy.
The 28-year-old star is currently on the European leg of her world tour, before she heads to Glastonbury next month for a headline set.
Adele recently premiered the video to her new single "Send My Love (To Your New Lover)" at the Billboard Music Awards.