The Grammy winner was forced to halt the performance when a 47-year-old woman suffered the heart condition and emergency services were called, reported Daily Mirror.
More than 95,000 fans had made their way to the ANZ stadium last night and had to clear a path to allow paramedics to get to the ill woman.
The fan was taken to a local hospital in a serious condition, and Adele seemed upset about what had happened.
Eyewitness Meg Rylance says she was sitting in the next row from the woman.
"She actually seemed really tearful," the concert-goer adds.
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