The romantic-drama stars Aishwarya Rai Bachchan, Ranbir Kapoor, Anushka Sharma and Fawad Khan.
"Ae Dil Hai Mushkil" is the first time when Pritam is composing music for a film directed by Johar.
The "Dilwale" hitmaker feels it is very easy to work with the producer-director as he is a very instinctive person who offers quick feedback.
"He is such an impromptu, instinctive person. It has been the easiest experience to work with him because he is so instinctive.
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On soundtracks in Johar-directed films being a hit always, Pritam said, "This (Ae Dil Hai Mushkil's music) too would be grand and romantic for sure. I am really looking forward to a great collaboration with Karan Johar."
This year, the 44-year-old composer will also reunite with filmmaker Anurag Basu for Ranbir Kapoor-Katrina Kaif starrer "Jagga Jasoos".
"Jagga Jasoos" will feature many tracks, making it the most difficult movie he has ever worked in.
"The number keeps on changing everyday, I also don't know how many songs. But there are lots of songs. I think 'Jagga Jasoos' is the most difficult film I have ever worked in or I will be ever working in. The situations are devised as musicals and it is getting really difficult to crack.
"Because (generally) we do one love song, wedding song, sad song. In all the Hindi films, we are given briefs like 'they are falling in love, painting the town' but in Jagga Jasoos the brief is very complicated and layered."
protagonist was not talking; just imagine doing a film where the leads don't talk properly. His films are always challenging but this is ten times more challenging than "Barfi". I am trying to cope up with it and hopefully, I pray we get through and do a good work."
Pritam will be seen mentoring aspiring singers on the upcoming season of the reality show "Sa Re Ga Ma Pa".
The "Bajrangi Bhaijaan" composer feels reality show contestants benefit "a lot" from such shows in gaining a foothold in Bollywood as it gives them a huge platform.
"Another benefit for us is when we need new singers, we go on YouTube and check them out. I don't have to wait for them to come to me."
The new instalment of the show, which returns after a hiatus of three years, will be hosted by the singer-actor Aditya Narayan. The show premieres on March 26 on Zee TV.