Aggarwal (373) proved no match for the world number 13 from Belarus and surrendered meekly 7-11 7-11 1-11 6-11 in the first round encounter of the main draw.
She was the only Indian entrant into the top-32 women's singles competition.
Earlier in the day, the pair of Achanta Sharath Kamal and Sanil Shetty was beaten by Ning Gao and Hu Li of Singapore 5-11 11-6 3-11 10-12 in their opening match of the main event.
No Indian women pairs could qualify for the main draw of the doubles event.
In the Under-21 boys' category matches played today, Desai (58) fought hard against Quentin Robinot (22) of France before going down 8-11 9-11 11-9 9-11, while Ghosh (28) was overwhelmed by China's Zhendong Fan (3) 2-11 6-11 10-12.
Ankita Das could not even clear the qualification-round hurdle in the girls' Under-21 section.