"Those who think that the problems of this world can be solved with isolationism or protectionism are terribly wrong," she told the German parliament ahead of the July 7-8 Group of 20 summit.
She acknowledged that even within export powerhouse Germany, there are anti-globalisation voices and critics against free-trade agreements.
"But protectionism isn't the answer," she said, adding that at the G20 summit in the northern city of Hamburg, Germany's biggest port, she would be seeking a "clear signal for open markets and against sealing off".
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