The study, published in the journal Human Reproduction, is the first to show that exposure to air pollution among teen girls (ages 14-18) is associated with slightly increased chances of menstrual irregularity.
"While air pollution exposures have been linked to cardiovascular and pulmonary disease, this study suggests there may be other systems, such as the reproductive endocrine system, that are affected as well," said Shruthi Mahalingaiah, from the Boston University School of Medicine in the US.
However, it was not known if air pollution was associated with menstrual cycle regularity, until now.
The researchers used health and location data gathered in the Nurses' Health Study 2 plus air pollution exposure metrics from the EPA air quality monitoring system to understand a participants' exposure during a particular time window.
They found exposure to air pollution in during high school was correlated with menstrual cycle irregularity.
"Implications on human disease may come through reducing emissions on a global and individual level," said Mahalingaiah.