According to traditional elders near Bardhere town in the southern Gedo region, at least two missiles struck vehicles believed to be carrying commanders of the Somali-led Al-Qaeda affiliate.
"We heard two big explosions and the information we are getting indicates that vehicles were targeted close to a Shebab military base," said Abdiwahab Ali, an elder at a village close to the scene of the attack.
"Village residents are telling us a missile fired from an aircraft struck a vehicle and a nearby military camp belonging to Shebab," said Hassan Gesle, another elder.
Regional government officials confirmed the air strike but were unable to give details of who was targeted.
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Ahmed Bare, Somali military officer in nearby Elwaq town, said that Shebab commanders have been leaving Bardhere, one of the few towns still held by the militants, ahead of a planned ground assault by Somali troops.
Last month Somalia's security agency claimed it carried out a night raid in Bardhere killing an unspecified number of Shebab commanders.
Also last month a Shebab assault on an African Union base in Lego left dozens of Burundian soldiers dead.