Syrian Prime Minister Wael al-Halqi said "terrorists" were killing townspeople, while Syrian state media said militants had looted and destroyed homes in the village of Zaara, which was previously controlled by the government.
Clashes between insurgents and pro-government forces continued into the afternoon as government or allied Russian aircraft pounded rebel positions, the Britain-based Syrian Observatory for Human Rights said, adding that seven militants were killed.
The Local Coordination Committees, an activist-run network, said the insurgents killed over 30 pro-government fighters in the clashes.
Syria's conflict began with peaceful protests against President Bashar Assad but escalated into a civil war after a brutal government crackdown and the rise of an armed insurgency. It became increasingly sectarian with the rise of Sunni insurgent groups and the arrival of Shiite militants from across the region to fight alongside Assad's government.
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The International Committee for the Red Cross had to cancel an aid convoy to the nearby town of al-Houla, citing security concerns. A spokesperson for the ICRC did not say whether it was related to the clashes in Zaara.
The 24-truck convoy with the Syrian Arab Red Crescent was to make the first aid delivery to the town since March, when aid reached 70,000 residents in the area for the first time since May 2015.