The actress, who has previously appeared in 'Joan of Arcadia' and 'House', will play Jenny in the hit CBS comedy, reported Ace Showbiz.
In the show's season 11 premiere, Jenny will come looking for her dad Charlie, only to find his house now occupied by Walden Schmidt (Ashton Kutcher). She moves from New York to LA for an acting career.
"She's somewhat of a chip off the old block. She's having a good time and doesn't care about the destruction left behind her. Decadence from the other side felt long overdue," 'Two and a Half Men' executive Chuck Lorre said.
His exit followed a highly-publicised video last year, in which he branded the series "filth" and urged people to stop watching.