The Syrian Observatory for Human Rights said Wednesday's strike destroyed a building being used as a headquarters and a prison by IS militants in Deir Ezzor province.
The strike on the village of Ghareebeh killed "at least 18 jihadist fighters and leaders, most of them non-Syrians and including an American," the Britain-based Observatory said.
Yesterday, the Observatory reported that at least five IS militants had been killed in that attack, and that the raid enabled some of the jail's prisoners to escape.