The 35-year-old actress revealed her anger on Instagram, saying she was joking about leaving the US.
"First of all the interview where I said I would move was in London and was said in jest. Not that anyone needs more than a headline to count something as official news," she wrote.
During an interview in September she said she was planning to move to Spain should Trump, 70, win the election.
"It's beyond my comprehension if Trump won. It's too crazy," she said at the time.
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Schumer went on writing, "Anyone saying pack your bags is just as disgusting as anyone who voted for this racist homophobic openly disrespectful woman abuser.
"Like the rest of us I am grieving today. My heart is in a million pieces. My heart breaks for my niece and my friends who are pregnant bringing children into the world right now."
Schumer then directly attacked those, who had voted for the Republican presidential candidate calling them "weak" and "misinformed".