Folman ("Waltz With Bashir", "The Congress") will write and helm a family-friendly animated film based on the girl's famous diary which has been published into a book and translated into many languages.
"Bringing the Anne Frank Diary to all screens is a fantastic opportunity and challenge," the Oscar-nominated director said in a statement. "There is a real need for new artistic material to keep the memory alive for younger generations."
The project is fully supported by Anne Frank Fonds Basel organisation which gives the filmmakers complete access to all of its archives. They are reportedly also negotiating the rights for the worldwide release, on all media and in all languages.
She wrote her life during World War II in a book given to her on her thirteenth birthday.
Her moving story has been a subject of several film and TV adaptations, including George Stevens' 1959 Oscar-winning "The Diary of Anne Frank".