Organisers in Manhattan carried signs in English and Spanish saying things like "Hate won't make us great," and chanted, "We are here to stay."
More than 1,000 people joined the march that started mid-afternoon and extended into the evening.
It was the latest in days of demonstrations across the country, and even throughout the world. Protests were held Sunday in Los Angeles, San Francisco, Philadelphia and more cities.
Several hundred protesters yesterday marched around Philadelphia's City Hall and then down Market Street to Independence Mall, carrying signs and chanting "Donald Trump has got to go!" and "This is what democracy looks like."
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By nightfall, a few hundred people marched across downtown San Francisco's main street, blocking traffic at an intersection when they held a sit-down protest.
Elsewhere in California, about 800 people marched through Sacramento and thousands others formed a human chain around the nearly 3.5-mile perimeter of Oakland's Lake Merritt.
Rallies in Oakland have at times become unruly, but those who came to the lake held hands and chanted, "We reject the president-elect."
The Portland Police Bureau said most protesters were cited for disorderly conduct and failing to obey an officer. Demonstrations also took place internationally.
On Saturday, a group of Mexicans at statue representing independence in Mexico City expressed their concerns about a possible wave of deportations. One school teacher said it would add to the "unrest" that's already in Mexico.
About 300 people protested Trump's election as the next American president outside the US Embassy near the landmark Brandenburg Gate in Berlin.
Mostly, the demonstrations were peaceful. However, in Portland, Oregon, a man was shot and wounded Saturday morning during a confrontation. Police arrested two teenagers in the shooting.