Mauricio Pochettino admitted his Tottenham stars are suffering from fatigue after they lost for the first time at their new stadium as Michail Antonio fired West Ham to a surprise 1-0 victory on Saturday.
Pochettino's side had won all four matches at their new ?1 billion Tottenham Hotspur stadium.
But Antonio's clinical second half strike ended that run as the West Ham winger became the first visiting player to score in the plush arena.
Third placed Tottenham's second defeat in their last three Premier League games put a dent in their bid to finish in the top four.
They hold a three-point lead over fourth placed Chelsea and are four points ahead of fifth placed Arsenal, with both team in action on Sunday.
It was a frustrating warm-up for Tottenham's Champions League semi-final first leg against Ajax in north London on Tuesday.
Blaming Tottenham's hectic fixture list for their defeat, Pochettino said:
"It was really tough today. We did not manage the ball properly. In the second half we conceded a lot of space for them to counter attack."
- Growing in confidence -
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Tottenham found it tougher to maintain any momentum in the second half, with Son's unsuccessful penalty appeal, after being bundled over by Arthur Masuaku, made more in hope than expectation. Manuel Pellegrini's team were growing in confidence and they ended
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