Israel's actions are "playing with fire, and will only ignite a religious war and shift the core of the conflict from politics to religion," Arab League chief Ahmed Abul Gheit said.
He was speaking at an urgent meeting of Arab foreign ministers in Cairo on the latest violence in Jerusalem.
"I invite the occupying state (Israel) to carefully learn the lessons from this crisis and the message it holds," Abul Gheit said in a televised speech.
Protests and deadly unrest have erupted in the days since Israel installed new metal detectors on July 16 outside the entrance to the Haram al-Sharif compound, known to Jews as the Temple Mount.
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Palestinians view the move as an attempt by Israel to assert further control over the site, which houses the revered Al-Aqsa mosque and the Dome of the Rock.
Israeli police and Palestinians clashed today as thousands of Muslim worshippers entered the compound, ending a boycott after Israel removed the new security measures installed after a July 14 attack killed two policemen.
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