The play has been written by Young Jean Lee and will be directed by Anna D Shapiro. The announcement was made by production company Second Stage Theatre, reported Variety.
Also starring Tom Skerritt, the play is set around Christmas Eve, and explores questions of identity and culture as a father and his three adult sons gather for the holidays.
The "Call Me by Your Name" actor will play one of the sons while Skerritt will play the role of the father.
The play will begin previews at the Hayes Theatre on June 29, 2018, before opening on July 23.