Last season's runners-up Arsenal and Steven Gerrard's Rangers have their sights fixed on the Europa League knockout phase Thursday with 19 clubs competing for the final 11 places.
Interim Arsenal boss Freddie Ljungberg will look to lead the Gunners into the last 32 after Unai Emery was sacked following last month's 2-1 home loss to Eintracht Frankfurt.
Monday's 3-1 victory at West Ham ended the club's worst winless run since 1977 and Arsenal just require a point at Standard Liege in Belgium to progress from Group F.
Rangers missed out on their first major silverware in almost a decade at the weekend following an agonising 1-0 defeat by Celtic in the Scottish League Cup final.
Gerrard's side dominated large parts of the game but were unable to find a way past an inspired Fraser Forster, who saved a second-half penalty from Alfredo Morelos.
Rangers are top of Group G and will advance if they avoid a second defeat of the competition to Swiss champions Young Boys.
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"We've got a huge game on Thursday and there's no better game to bounce back," Gerrard said.
"We have to soak it up, remember it and be ready to go and give ourselves another opportunity. That type of performance will get us where we want to get to.
"It's raw right now but this is football at the top. We'll suffer and then we'll bounce back."
Fixtures:
Groups A-F (kick-offs 1755 GMT)
Group A:
APOEL (CYP) v Sevilla (ESP)
Qarabag (AZE) v Dudelange (LUX)
Group B:
FC Copenhagen (DEN) v Malmo (SWE)
Dynamo Kiev (UKR) v Lugano (SUI)
Group C:
FC Basel (SUI) v Trabzonspor (TUR)
Getafe (ESP) v Krasnodar (RUS)
Group D:
LASK (AUT) v Sporting Lisbon (POR)
PSV Eindhoven (NED) v Rosenborg (NOR)
Group E:
CFR Cluj (ROM) v Celtic (SCO)
Rennes (FRA) v Lazio (ITA)
Group F:
Standard Liege (BEL) v Arsenal (ENG)
Eintracht Frankfurt (GER) v Vitoria Guimaraes (POR)
Groups G-L (kick-offs 2000 GMT)
Group G:
Rangers (SCO) v Young Boys (SUI)
Porto (POR) v Feyenoord (NED)
Group H:
Espanyol (ESP) v CSKA Moscow (RUS)
Ludogorets (BUL) v Ferencvaros (HUN)
Group I:
Wolfsburg (GER) v Saint-Etienne (FRA)
Gent (BEL) v Olexandriya (UKR)
Group J:
Borussia Moenchengladbach (GER) v Istanbul Basaksehir (TUR)
Roma (ITA) v Wolfsberg (AUT)
Group K:
Wolves (ENG) v Besiktas (TUR)
Slovan Bratislava (SVK) v Braga (POR)
Group L:
Manchester United (ENG) v AZ Alkmaar (NED)