The losses tracked a sell-off in tourism-linked firms in the United States and Europe as already delicate nerves were frayed on trading floors after Turkey shot down the Russian warplane on the Syrian border.
The incident also sent oil prices up on concern about supplies.
While Ankara said it acted after the jet entered its airspace, Russian President Vladimir Putin called it a "stab in the back" and warned of serious consequences. Moscow insists the plane was in Syrian territory.
"A spreading and escalation in recent terror attacks and now the downing of a Russian warplane by Turkey are raising concerns of the possible unforeseen spillover impacts of Middle East conflicts," Con Williams, a rural economist at ANZ Bank New Zealand, said in a note to clients.
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"The accumulation of these events is now beginning to have an influence on global markets," he added, according to Bloomberg News.
The city of Brussels will stay at the highest security threat level for another week over fears of an imminent attack.
On Monday Washington issued a world travel alert, warning Americans of "increased terrorist threats" and saying they should "exercise vigilance when in public places or using transportation".
Airline shares fell in Asia. Sydney-listed Qantas was down 1.6 per cent, Cathay Pacific in Hong Kong shed two per cent, ANA lost 1.7 per cent in Tokyo and Seoul-listed Korean Air Lines was 0.7 per cent off.
However, while stock markets in London, Frankfurt and Paris all ended in the red, the uptick in crude helped energy firms push Wall Street to a positive close.