Japanese stocks rose after a slew of economic data releases but other regional indexes were mixed.
Japan's benchmark Nikkei 225 index rose 1.1 per cent to 17,437.69 while South Korea's Kospi slipped 0.2 per cent to 1,978.85.
Hong Kong's Hang Seng edged 0.1 percent lower to 23,978.58 while in mainland China the Shanghai Composite Index gained 0.7 per cent to 2,649.57. Australia's S&P/ASX 200 tumbled 1.4 percent to 4,323.10.
Benchmarks in Taiwan, Singapore and the Philippines rose while in Thailand, Indonesia and New Zealand they fell.
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Benchmark US crude oil tumbled 6.5 per cent, or USD 4.82, to USD 68.86 a barrel in electronic trading on the New York Mercantile Exchange.
Brent crude, used to price oil sold on international markets, slipped 9 cents to USD 72.49 after losing about USD 5 in the previous session.
Oil-related stocks were the big losers following the slide in crude prices. Chinese state owned oil giant CNOOC, the country's biggest crude producer, plunged 5.3 per cent while Petrochina slid 3.3 per cent and Sinopec fell 3 per cent.
A raft of data releases gave mixed signs about the state of Asia's second biggest economy but the Nikkei surged nonetheless, a sign that investors thought the situation wasn't getting any worse and may even be stabilizing after Prime Minister Shinzo Abe renewed stimulus efforts. Inflation edged lower while industrial output edged up from the month before and unemployment eased slightly.
US markets were closed yesterday for the Thanksgiving holiday.
The euro slipped to USD 1.2447 from USD 1.2453 in late trading yesterday. The dollar strengthened to 118.29 yen from 118.12 yen.