The trend poses a new and worrying threat in a tech-savvy region where products derived from endangered species are sought for traditional medicines and exotic animals are prized as pets, said wildlife-trade monitor Traffic and conservation group WWF.
"Traders are clearly moving to non-conventional methods of sale such as utilising online portals and social media in order to evade detection, reach a broader audience and increase transaction efficiency and convenience," Traffic said in a report released to coincide with today's World Wildlife Day.
Traffic said in a single month in China last year, thousands of ivory products, 77 whole rhino horns and large numbers of endangered birds were found advertised for sale on sites such as QQ and WeChat, which are popular in China.
"The wildlife trade network is getting smarter and more sophisticated," WWF Malaysia director Dionysius Sharma told AFP.
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"We need to be one step ahead and come up with creative solutions to eradicate this problem."
Traffic's report focused heavily on Malaysia, where Facebook use is high.
During the observation period, scores of traders put up more than 200 individual posts offering to sell live wild animals ranging from rare birds to orangutans and sun bears, it said.
Often, photos of for-sale animals were uploaded to Facebook, Instagram, and other sites, while bargaining took place over platforms like WhatsApp in Malaysia and BlackBerry Messenger in Indonesia.
"Trading appears to be very relaxed and traders will happily provide their contact details and will sometimes offer to deliver the animal to the buyer's home address," said the report.