The Syrian Observatory for Human Rights said the strikes on the market in Idlib province's Maaret al-Numan were probably carried out by regime forces.
Much of Idlib province, including Maaret al-Numan, is controlled by Hayat Tahrir al-Sham (HTS), a group led by Al- Qaeda's former Syria affiliate.
Idlib is one of four so-called "de-escalation" zones under a deal brokered by Russia, Turkey and Iran in May.
However, the HTS is not party to the agreement.
Observatory head Rami Abdel Rahman said "military aircraft" had targeted the market in Maaret al-Numan, blaming the regime for the strike.
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The Observatory relies on a network of sources inside Syria, and says it determines whose planes carry out raids according to type, location, flight patterns and munitions used.
The Observatory said that on Friday and yesterday, at least 13 civilians died in suspected regime air strikes around Khan Sheikhun, the site of a deadly April chemical attack.
Despite months of relative calm in Idlib, Syrian regime and Russian forces have in recent weeks carried out air raids across the province, killing dozens of civilians, according to the Observatory.
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