He was 69.
Fred Toczek tells The Associated Press that Ramis died today from complications of autoimmune inflammatory disease. Ramis is best known for his roles in the comedies "Ghostbusters" and "Stripes."
According to Biography.Com, Ramis co-wrote "Ghostbusters," in which he appeared with fellow Second City alums Dan Aykroyd and Bill Murray.
The website says he also co-wrote "National Lampoon's Animal House" and "Meatballs" and directed such films as "Caddyshack" and "Groundhog Day.