Relentless Rafael Nadal will aim to snuff out the challenge of young giant-killer Frances Tiafoe Tuesday, while young Greek Stefanos Tsitsipas has eyes on a maiden Australian open semi-final after knocking out Roger Federer.
The Australian Open hits the quarter-final stage in Melbourne with 17-time Grand Slam winner Nadal emerging as a strong title favourite.
The Spaniard has not dropped a set and demolished former world number four Tomas Berdych 6-0, 6-1, 7-6 (7/4) in the fourth round in an awesome display.
Lying in his path is American Tiafoe who has already accounted for the fifth seed Kevin Anderson and become a fans' favourite with his exuberant LeBron James style celebrations and inspiring life story.
The son of immigrants from Sierra Leone, Tiafoe turned 21 on Sunday and celebrated his birthday by beating 20th seed Grigor Dimitrov to reach a Slam quarter-final for the first time.
"I wasn't a normal tennis story," he told reporters, revealing he had already managed to buy his mother a house in Maryland and help his janitor dad.
"The beginning of my career I was trying to do everything for my family. Obviously now I put them in a great place. Now I'm trying to do it for me.
"I'm so excited to play Rafa. We're going to have some fun, going to have some long rallies."
- 'He's dangerous': Nadal -
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"He's a very dynamic player, aggressive one. Of course, he's dangerous. He's in quarter-finals."
"I'm really pumped and excited to be competing in the quarter-finals. I'm really waiting for that moment."
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