"Yogi Adityanath should first get married and prove his masculinity," Khan told reporters on the sidelines of an event here last night.
Replying to question on whether he considered all sages in the country did not possess masculinity, Khan said, "they are frustrated."
"How would a Mahant know what love is ... He should first get married and help in growth of generation," he said.
He said Khan has lost his mental balance and needed medical attention.
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Meanwhile in Lucknow, state BJP chief Keshav Prasad Maurya said such a statement only indicated Khan's mental bankruptcy.
"The SP should apologise for the same," he said, adding the minister has degraded the dignity of sages.
The remarks also invited wrath of various Hindu outfits who held a dharna against Khan and burnt his effigy in protest.
Khan also attacked another BJP MP Sakshi Maharaj and said there are many serious cases against him which are condemnable.