Only two points separate the two teams.
Dempo earned a goalless draw against United SC, while Mohun Bagan had to come from behind to hold Mumbai FC as both clubs have managed only 11 goals from 13 games.
Mohun Bagan have struggled to find consistency in Karim Bencherifa's second spell and managed to win back-to-back matches only once this season.
Despite having one of the all time best I-League strikers in Odafa Okolie, Mohun Bagan are yet to fire up their campaign.
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But Bencherifa would take heart from the fact that his side earned a point in the last game despite lagging behind.
If they earn all three points against Dempo tomorrow, Mohun Bagan could end in top six.
"I am looking for consistency. Nobody has run away with the I-League yet. The league is still wide open and we have a good realistic chance to go into better positions," Bencherifa said.
The Goan club have kept clean sheets in their last two away matches in Kolkata but their youngsters will have their task cut out against Odafa and company.