The bandh called by around 20 outfits, including Vaiko-led MDMK, evoked lukewarm response across the state while it was total in the neighbouring Union Territory of Puducherry, according to reports received here.
Normal life remained unaffected in Tamil Nadu with buses, autorickshaws, taxies and private vehicles plying as usual and schools and colleges and offices functioning normally.
Shop owners who had downed shutters in several areas in the morning resumed operations by afternoon, reports said.
Police, who had made elaborate security arrangements to maintain law and order, detained more than 2,500 protesters, including MDMK chief Vaiko for staging rail and road blockade.
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Around 20 outfits and parties including MDMK, Thanthai Periyar Dravida Kazhagam, Manithaneya Makkal Katchi and CPI, had called the bandh demanding "total boycott" of Commonwealth Heads of Government Meeting being held in Colombo from November 15 and seeking suspension of Sri Lanka from the group for alleged war crimes against ethnic Tamils.
Vaiko, along with about 300 party activists, was detained for blocking Vaigai Express train in Madurai while more than 1,200 protesters were taken into custody for picketing railway stations in Coimbatore, Tirupur and Nilgiris districts.
Cadres of Manithaneya Makkal Katchi were held for staging rail roko at various railway stations in Chennai, where life was normal. Members of Students Federation of Tamil Eelam boycotted classes.
Puducherry observed "total" bandh where majority of shops and business establishments remained closed and public and private transport kept off the roads.
Most of the private schools in Puducherry declared a holiday and cinema houses suspended shows.
Tamil Nadu Assembly is holding an emergent special session to discuss India's participation in CHOGM and is expected to adopt a resolution urging the Centre to heed to its October 24 resolution which sought a "total boycott" of the event by India.