Barcelona's hopes of winning a fifth consecutive Copa del Rey were dented on Wednesday as they were beaten 2-0 by Sevilla in the first leg of the quarter-finals.
Lionel Messi was rested and Luis Suarez left on the bench as Kevin-Prince Boateng made his debut for Barca in a match that Sevilla might even have been disappointed not to win by more.
Even so, Pablo Sarabia and Wissam Ben Yedder each scored in the second half at the Ramon Sanchez Pizjuan to leave their opponents facing an uphill task if they are to rescue next week's second leg.
"We played a great game, it's a shame it doesn't settle the tie," said Sevilla coach Pablo Machin.
"In Barcelona, anything can happen. They have turned around bigger defeats than this." Ben Yedder celebrated his goal by unveiling a t-shirt in support of Argentine striker Emiliano Sala, the player who is feared to have died in a plane crash on his way to join new club Cardiff City in Wales.
"Para mi hermano fuerza E. Sala", the message read, meaning, "For my brother, be strong".
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Barcelona had thrashed Sevilla 5-0 in last year's final, when Andres Iniesta delivered a masterclass in what was one of his final appearances for the club.
Winning a domestic double, however, did little to ease the disappointment of crashing out of the Champions League and Ernesto Valverde is clearly keener to rotate in the Copa del Rey this season.
Messi and Sergio Busquets were left out completely while Luis Suarez, Philippe Coutinho and Jordi Alba all started on the bench, only to come on as substitutes in the second half.
"I thought it was for the best," Valverde said. "But when you make changes you take risks."
"He is an exciting signing for the club," Valverde said. "He is for both the future and the present."
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