The seriousness of the global problem was highlighted when US President Barack Obama announced a plan last month to make millions of acres (hectares) of land more bee-friendly.
Loss of habitat, the increasing use of pesticides and growing vulnerability to disease are blamed by many critics for the plight of the honey bees.
The environmental group Greenpeace, which has launched a campaign to save the insects, says that 70 out of the top 100 human food crops, which supply about 90 per cent of the world's nutrition, are pollinated by bees.
"It's exactly the same as around the world, the bees are sick of humans and the pressures and the stresses humans are putting on them," said Allsopp.
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"In the past they were less vulnerable because they weren't stressed by intensive bee-keeping and pesticides and pollution."
The foulbrood hitting South Africa is the American strain of the disease, he said. The country's bees have previously coped with the European version.
"It is a ticking time bomb. Every colony that I've looked at that has clinical foulbrood has died, and we're not seeing colonies recover."
When honey bee farmer Brendan Ashley-Cooper discovered foulbrood in his colonies in 2009, he knew the worst was yet to come.
"We thought we were going to have this major explosion of foulbrood," said Ashley-Cooper, a 44-year-old based in Cape Town. "I didn't know what to do, I didn't know what the extent of it was. I was just worried about the bees."