Researchers at the University of Rochester Medical Center tapped into the National Survey of Midlife Development in the US (MIDUS) database, a survey of over 1,000 Americans from across the country.
The database contains information on disease-related bio-markers (like cholesterol levels and body-mass index [BMI] scores) as well as personality traits, including neuroticism.
Neuroticism is typically associated with a number of unhealthy traits.
"Most studies find that a higher level of neuroticism is associated with increased substance abuse, higher inflammation and increased risk of mortality," Livescience quoted Dr Nicholas Turiano of the University of Rochester Medical Center, as telling Today.Com.
However, the neurotics in the MIDUS database who also had conscientious personality traits - organised, hard-working, responsible and self-controlled - showed some interesting health advantages.
Their levels of Interleukin 6 (IL-6), a biomarker for chronic disease and inflammation, were significantly lower than the IL-6 levels found in other personality types.
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The conscientious neurotics also had lower average BMI scores and were diagnosed with fewer overall chronic health conditions than other personality types.
"[W]hat we found was that when people are high both in neuroticism and conscientiousness, the conscientiousness buffers the negative effects of neuroticism," Turiano said.
According to Today.Com, more research is needed into the link between personality traits and health before it can be said that "healthy neuroticism" confers any real physical benefits.