In a hard-hitting reply, laced with emotion and anger, she forcefully defended the action against students of JNU saying Kanhaiya Kumar and some other students had been found indulging in anti-national activities by the JNU authorities themselves.
The debate, which was advanced in the Lok Sabha from tomorrow after Congress insisted on it, was often acrimonious with attacks and counter-attacks with each side giving its version of nationalism and patriotism.
Government fielded two other heavyweights--Home Minister Rajnath Singh, Urban Development M Venkaiah Naidu--besides Irani to take on a combined opposition.
Irani's aggression drew praise from Prime Minister Narendra Modi who tweeted: "satyamev jayate" along with the video of her speech. Singh, who took the floor after Irani, said any amount of praise for her would not be enough.
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Facing flak over slapping sedition charges on Kanhaiya Kumar and others, Singh said the issue should now be left to the courts to decide. Even a BJP ally TDP voiced concern over the issue, saying sedition charge was a harsh action.
He also said that that government has always maintained that JNU is a centre of excellence and it had never described it as an "anti-national centre".
The opposition had gunned for Irani and Labour Minister Dattatreya, whose letters to her have been blamed for the suicide of dalit scholar Rohith Vemula in the Hyderabad Central University, and demanded action against them.
Members of the Congress, Left parties and Trinamool Congress staged a walk out in the wake of her strident attack on them in which she rejected the charge of saffronisation of education.
Contending that she was being targeted for contesting
against Rahul in Amethi in last Lok Sabha polls, Irani invoked Indira Gandhi and said even "her son" (Rajiv) had lost power but still he did not do what "you (Rahul) are doing" of joining the protests of "anti-nationals".
The HRD minister made an emotional pitch on Vemula's suicide, insisting that her ministry had no role in his death and the deceased himself had said in his suicide note that nobody should be held responsible for his action.
During last 20 months as Minister, Irani said she tried to do justice to students by trying to address their complaints without asking for their "caste or religion".
Referring to attack on the government as being "anti-minority", she gave examples of helping students, including one Muslin boy from Kashmir who had apprised her about not getting scholarship.
She also named a number of MPs, including Pappu Yadav, Saugata Roy, Assadudin Owaisi and Shashi Tharoor, whom she had helped after they made requests for school admissions.
Rejecting the charge of saffronising education, she said, she would quit politics if it was established she made any attempt to do so.
"Help me build the nation, not destroy it from within," she said stressing, "I respect your patriotism, don't demean mine... I have my idea of India...Don't demean it."
Citing documents, she said, report by JNU's security people observed that some students were indulging in anti-national sloganeering even though the students had sought permission to hold a "poetry" event.
Those involved in the programme which include Umar Khalid, Kanhayia Kumar and others, she said, were suspended by the JNU authorities though they were allowed to stay on the campus till completion of the inquiry.
Hanging of Afzal Guru was described by the activists as "judicial murder", she said, adding it amounted to rising against Supreme Court and the Indian state.