The 40-year-old will follow in the footsteps of fellow filmmaker Quentin Tarantino when he receives the Career Achievement Award, The Hollywood Reporter said.
Casting director Lora Kennedy, who worked with Affleck on his movie "Argo", will also take home a trophy.
This year's Artios Awards, which celebrate outstanding film, TV and theatre casting, will also recognise actor and playwright Harvey Fierstein.
"Ben is one of the first all encompassing filmmakers we have honored (sic). Ben is a consummate actor, director, writer and producer. The Artios Awards are known for celebrating casting directors, who can challenge audiences with their original and bold ideas, and this applies to Lora, whose body of work exemplifies this," Pam Dixon, CSA President said in a statement.
The awards will be handed out at twin ceremonies in New York and Los Angeles on October 29.