The "Night at the Museum" actor stars as Brad Sloan, a middle-aged man left miserable by constantly comparing himself to his successful friends.
Stiller said he was drawn to the movie for tackling something that isn't talked about in Hollywood, reported Collider.
"I think Mike is just an amazing writer, and he finds the truth in the scenes, and the places we don't necessarily want to go to, the uncomfortable places, and then he finds the humour in that," Stiller said.