Acting on information that the four persons were involved in cricket betting, the arrest was made by Mangaluru City Crime Branch (CCB) yesterday, police said.
The four accused were picked up from a car near the jail road from where they were taking bets on the outcome of an ongoing match, they said.
The arrested persons have been identified as Sreejith Shetty (27), Prajeeth (27), Prasanth (33) and Rajesh, residing in and around the city.