During a stop in Detroit, the singer dedicated her performance of "Halo" to families of those dead in the tragic incident happening last weekend, reported Ace Showbiz.
Beyonce, 34, described it as "a song about love" when introducing the track in front of the crowd packing the Ford Field.
"I'd like to dedicate ('Halo') to all of the family members who lost family members in Florida," she said before starting the song.
At the same show in Detroit, DJ Khaled who's been opening for the Queen invited the Motor City's own Dej Loaf during his set.