Harry said his whole family felt "guilty" ever since Winehouse's death in 2011 at the age of 27, reported Female First.
"They seemed hell-bent on destroying each other and didn't care about dragging others down with them. It was like watching two speeding trains hurtle towards each other before a violent crash," he said of their relationship.
"I felt guilty because everyone knows it was Blake who introduced Amy to hard drugs. I didn't speak to him for about two years because I blamed him for so many things. I didn't hate him. I just wanted Amy to be still alive. We got back in touch only a couple of weeks ago. It destroyed our family.