The accusations that Qatar paid for votes when FIFA chose Qatar in 2020 will be discussed at the two-day Congress, the embattled 78-year-old Swiss official said.
The growing scandal has threatened to taint the opening of the latest World Cup in Sao Paulo on Thursday.
FIFA faces mounting pressure as five of its six major sponsors have called for a thorough investigation of the allegations largely made by the British media.
Blatter hit out at the "storm against FIFA" over the 2022 World Cup and the "discrimination and racism" at the heart of the attacks. He said the allegations "really make me sad".
More From This Section
CAF members -- who along with their long-time president Issa Hayatou have been accused in British media of accepting Qatar's money -- gave Blatter a rousing reception and also slammed the allegations.
"(CAF) condemns the strategy of using African sport movements and its leaders as scapegoats by those who are trying, at all costs, to acquire a good conscience for themselves," it said in a statement.
Blatter was equally defiant at the Asian Football Confederation adding that "I still have the fire inside" to lead FIFA.
Blatter's attack on the corruption charges echoed those of Asia's top Olympic official Kuwaiti Sheikh Ahmad al-Sabah, who said last week that the allegations were a racist attack on Arabs.
"We will confront all such acts of racism and we will stand with Qatar so that no-one removes its right to organise the 2022 World Cup in Doha," said the Sheikh, president of the Olympic Council of Asia and a highly-influential figure within the International Olympic Committee (IOC).