The unseeded Indo-Pak pair put up a stiff resistance before losing 7-6(7) 5-7 7-10 against the top seeds Nenad Zimonjic and Daniel Nestor.
Earlier, Somdev Devvarman had also lost in the doubles quarterfinals with Croatian partner Ante Pavic.
Somdev had also made a first-round exit in the singles event, his fifth straight opening-round loss in singles.