Random House publisher announced it has signed a book deal by Arquette, 46, who won an Academy Award for "Boyhood", reported Us magazine.
The memoir will deal with "her unconventional family, being a single mother at the age of 20, and her experience as a woman in Hollywood," according to the publisher.
No title or publication date revealed yet.
"Over the years, the public has come to know aspects of me through my roles in film and television. Writing a memoir will be a new and intimate artistic journey for me, and I hope to bring to it the same honesty I have always sought to bring to my work as an actor," Arquette said, in a statement released by the publisher.