Hussey continued his rich form and scored his 95 off just 59 balls during which he struck as many as 11 boundaries and two sixes.
KKR captain Gautam Gambhir's decision to field first after winning the toss backfired as openers Hussey and Wriddhiman Saha, who replaced Murali Vijay, sent the Kolkata bowlers for a leatherhunt to share 103 runs in just 66 balls.
Both Hussey and Saha were aggressive from the onset and did not spare a single KKR bowler.
Saha matched his partner stroke-for-stroke as he hit Shami Ahmed fot two fours and a six in the next over.
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Mystery spinner Sunil Narine and Jacques Kallis also came under duo's wrath as KKR reached 100 in the 10th over.
Hussey brought up his fifty in just 31 balls with the help of seven fours and one six.
KKR finally tasted a success in the 11th over when Saha was caught at midwicket by Eoin Morgan off Rajat Bhatia (1/31) but not before the diminutive Bengal wicketkeeper struck four boundaries and two huge sixes during his 23-ball 39-run knock.
Hussey and Raina added quick 55 runs off 34 balls for the second wicket before the former departed.
Hussey was unlucky to have missed out on a century as he fell just five runs short off the three-figure mark, caught at deep midwicket by Debabrata Das off Narine (1/35).
Raina also played a good hand, scoring his 44 off just 25 deliveries before he was run out.
Skipper Mahendra Singh Dhoni chipped in with a useful 18 off 12 balls towards the end to help CSK reach the 200-run mark.