Jaitley had yesterday urged the Kerala government to put an end to the "politics of annihilation" and allow the opposition to function freely.
Karat, who was here to attend a party meet, told reporters that the Union finance minister's speech in Thiruvananthapuram was beneath the dignity of a central minister and claimed that it had provoked the people of Kerala to trigger an unrest in the state.
She alleged that since the BJP had "failed to break" the CPI(M) "through money and muscle power" in Kerala, it was now resorting to killing the cadre of the Left party "with the help of the RSS".
"Records show that political killings have increased in a state like Uttar Pradesh among others," she claimed.