The House of Commons' Culture, Media and Sport Committee said it would investigate concerns about the public being swayed by propaganda and untruths.
"The growing phenomenon of fake news is a threat to democracy and undermines confidence in the media in general. Just as major tech companies have accepted they have a social responsibility to combat piracy online and the illegal sharing of content, they also need to help address the spreading of fake news," said committee chair Damian Collins.
The cross-party MPs will investigate whether the way advertising is bought, sold and placed online has encouraged the growth of fake news.
They also want to address the responsibility of search engines and social media to stop spreading it.
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The committee is seeking written submissions from interested parties by the start of March and is expected to hold hearings in due course.
The issue was thrown into the spotlight especially during the US presidential campaign, when fake news like the Pope supporting Donald Trump gained social media traction.
Stanford University had carried out research which suggested that fabricated news stories favouring Trump were shared 30 million times.
However, new research suggests that online hoaxes and propaganda may have only had limited impact in the US presidential election.
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