The actress/model will guest star in an episode of the FOX anthology series slated to air on December 13, reported Ace Showbiz.
The 51-year-old beauty, who is best known for her roles in "The Blue Lagoon" and Franco Zeffirelli's "Endless Love" among others, will play Dr Scarlet Lovin, a television doctor in the vein of Dr Oz who happens to be a fan of the Chanels, Entertainment Weekly reported.
Some famous stars have appeared in both seasons of "Scream Queens". In the first season, Ariana Grande starred as Chanel #2 and Nick Jonas appeared as Boone Clemens. In season 2, Colton Haynes played the role of Tyler.