Scientists from Sydney's Garvan Institute of Medical Research in Australia measured brown fat activity and blood glucose continuously in real time in study participants, and found that individuals with more brown fat had smaller fluctuations in blood sugar.
The findings open new avenues for diabetes therapies that target brown fat.
The incidence of type 2 diabetes, which is characterised by high blood sugar, is reaching epidemic proportions worldwide, researchers said.
Unlike white fat, which primarily stores energy, brown fat burns energy - often in remarkably large amounts. Sitting just above the collarbone and in the neck, brown fat acts like a heat generator, helping to keep us warm by burning sugar and fat, they said.
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"Previously, we showed that individuals with large brown fat stores tend to be lean and have lower blood glucose - and now, we have uncovered a potential link between brown fat activity and blood glucose variations," Lee said.
Researchers studied a group of 15 healthy adults over 12 hours. They found that blood glucose levels and heat production by brown fat were closely related, tracking together over time.
In contrast, brown fat activity rose only in response to an increase in blood glucose among those with less brown fat, and interestingly, their glucose fluctuations were greater. Individuals with no detectable brown fat had the widest fluctuations in blood glucose.
"Our findings indicate that brown fat might act as a 'glucose buffer', lessening the variation in blood glucose and potentially diminishing metabolic stresses that could increase the risk of diabetes," said Lee.
"Brown fat sits just under the skin, and it heats up when it is active. So, measuring skin temperature at the collarbone can allow us to estimate brown fat activity," said Lee.
"We speculate that this early morning temperature boost may have an evolutionary origin, generating heat and preparing our ancestors for hunting and gathering in the cold as the day begins," he said.
The findings were published in the journal Cell Metabolism.