The Civil Protection office in the city of Trento said none of the injuries was serious in the this morning accident on the A22 Autostrada.
The injured were treated in emergency rooms in local hospitals. Their ages ranged from 17 to 19.
The Italian news agency ANSA said the bus ended up on its side. It said the teenagers, 35 in all, had been heading home to Bremerhaven, Germany.
Civil Protection said the uninjured teenagers were taken to a local gym.